A COMBINED STUDY OF THE LIPID SPECTRUM AND CYTOKINE PROFILE IN SILICOSIS CORONARY HEART DISEASE AND ARTERIAL HYPERTENSION

Occupational disease of workers-mining remains the highest national average. Obtaining and monitoring information about the Republic of Uzbekistan is one of the most important tasks facing the management of the Republic of Uzbekistan and the health care system. As for the death and disability of the working-age population, vascular diseases take the main place, and arterial hypertension is the most widespread. It has been collected by many people in different countries and people. Reasons for the exacerbation of the disease arterial hypertension (AH) and related to it are diverse. For this, in order to come up with the most effective methods of combating them, it is necessary to take them in connection with various things, ethnic means, and professions. Thus, high-loading blue load as strong labor workers and miners (Bodarev OI, Bugaeva MS, 2015). We discuss in this narrative review a number of biochemical (lipid spectrum) and pro- and anti-inflammatory cytokines (TNF (tumour necrosis factor-α), IL-8 (interleukin-8)) biomarkers that have great potential for use in the management of silicosis. Research has indicated that the aforementioned markers hold great promise in assessing the advancement of early diagnosis in silicosis and are a viable substitute for radiography. Lipid spectrum biochemistry in silicosis Cardiovascular disorders play a major role in predicting development risk. In order to assess the accuracy of the biomarkers that have been provided, we believe that a multicentric investigation including large subject populations is required to assess these biomarkers in relation to work history, histological examination, imaging signals, and pulmonary function tests.